Current status of pathogen inactivation methods
نویسندگان
چکیده
منابع مشابه
Bacterial contamination of platelet concentrates: pathogen detection and inactivation methods
Whereas the reduction of transfusion related viral transmission has been a priority during the last decade, bacterial infection transmitted by transfusion still remains associated to a high morbidity and mortality, and constitutes the most frequent infectious risk of transfusion. This problem especially concerns platelet concentrates because of their favorable bacterial growth conditions. This ...
متن کاملPathogen inactivation: coming of age.
PURPOSE OF REVIEW In the past 20 years, several pathogen inactivation technologies have been developed to be applied to blood components. This review is intended to summarize the data currently available about the technologies and the clinical use of products inactivated by those techniques. RECENT FINDINGS Technologies for inactivating pathogens in plasma and platelets are available, and are...
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The residual risk of transfusion transmitted infection (TTI) had been decreased greatly since the donor screening methods, especially the nucleic acid testing (NAT), were introduced. NAT can shorten the period between infection and detection (window period) to several days after infection [1]. However, transfusion safety still faces challenges due to limitations of test sensitivity and more imp...
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Submit Manuscript | http://medcraveonline.com have proven to be effective against numerous bacteria, viruses, and parasites. Two main systems have emerged to treat platelet concentrates: treatment with psoralen ultraviolet A (UVA) light and treatment with riboflavin (vitamin B2) plus ultraviolet B (UVB) light, both targeting the nucleic acids of pathogens. The ability of the Mirasol PRT system ...
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ژورنال
عنوان ژورنال: ISBT Science Series
سال: 2010
ISSN: 1751-2816,1751-2824
DOI: 10.1111/j.1751-2824.2010.01370.x